Now I know that so long as we have social inequality we shall have snobs; we shall have men who bully and truckle, and women who snub and crawl. I know that it is futile to, spurn them, or lash them for trying to get on in the world, and that the world is what it must be from the selfish motives which underlie our economic life.William Dean Howells
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We've long suspected that genomic changes underlie cancer risk, but that knowledge hasn't translated yet into a broadly applicable way to identify individuals most at risk. The BRCA1 and BRCA2 genes implicated in breast and ovarian cancers are great examples, but they are applicable only to a small percentage - less than one percent - of women.Andrew Feinberg
We have shown that a gene called p11 is involved in the multiple complex changes that underlie depression. Our findings demonstrate that patients with depression, and mice that model this disease, have decreased levels of p11 protein, and they suggest that drugs that increase p11 are likely to have anti-depressant properties.Per Svenningsson