There are many factors involved in disease progression, and the type of virus is one of them. Our work may help us tease out what about this particular virus causes disease progression, and that may help us figure out how to stop it, either by preventing the spread, or blocking the mechanism to keep it from being so pathogenic.

Knowing a person's HIV subtype is important for the management of the infection because the disease can progress more rapidly in those infected with subtype D … than in those with other subtypes.

Also that mucosal layer does not have the thick keratin (skin) that the outside skin of the foreskin has.