These results were pivotal in our decision to move forward with a Phase 3 [clinical trial] program, the final stage in clinical development, ... If this program is successful, this new approach could change the way physicians manage cholesterol and reduce further the risk of atherosclerosis in their patients.

In view of the widespread commentary surrounding Viagra, we believe it is prudent and responsible to restate the appropriate use of this breakthrough medicine as well as to caution against inappropriate use.

At the same time, as is true with any medicine, all benefits and risks need to be considered by physicians when treating their patients. This communication is intended to reinforce our commitment to share information with physicians about our product.