It leaves the brain short-circuited. It's a very bad disease that normally progresses to death within a few months unless we can reverse the immune suppression.

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This drug is a good example of the potential of developing drugs with very specific biological targets in mind. But this experience also reminds us that there are a lot of hidden icebergs in the ocean we're navigating, and we're going to bump up against those icebergs and have to work out ways to navigate around them.

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