It's a way to get the highest potency but the lowest toxicity. You can call it a 'smart tumor bomb.' Even though you'll still get some toxicity, it is much, much lower compared to regular chemotherapy and the potency is much, much higher.
Jason Zhang
17 quotes about toxicity follow in order of popularity. Be sure to bookmark and share your favorites!
We are extremely pleased that data from our Phase III psoriasis trials of ISA247 will be presented to audiences that represent both dermatology and transplantation. We continue to be encouraged by the data generated in the SPIRIT extension trial and we believe ISA247 will continue to demonstrate continued efficacy with minimal toxicity.
Dr. Randall Yatscoff
This little boy did not die of diphenhydramine toxicity. That's not what happened.
Robert Stephens
It seemed to us like a disaster waiting to happen. The unique benefits of the drug were outweighed by the need to constantly monitor for liver toxicity.
Peter Lurie
We are not saying we are confident these drugs will not cause liver toxicity.
Dr. Janet Woodcock
So you pick out a small lesion in the lung and really focus on it, pinpoint the treatment as opposed to treating a larger area, ... It reduces toxicity and allows you to deliver a very high dose. That's basically where radiation is evolving.
David Greenwald
So far to date, the drug has not shown any significant toxicity in animal species in which we've administered the drug.
Amy Patick
I think the most exciting benefit is just the fact that we're now able to do a treatment that in the past has had quite a bit of toxicity for patients. It will result in increased dose intensity to the tumor, and fewer overall side effects for the patient.
Albert Koong
Non-toxicity is good on the manufacturing end, for users, and for the environment when the product's useful life is over.
Michael Rendon
You couldn't ethically give these (high) doses by the oral route because of toxicity, and because of the effect on the immune system. They could potentially depress the immune system and leave the patient open to opportunistic infections that could be fatal.
Aldo T. Iacono
We're trying to convince them to leave without using force, ... We tell them about the toxicity of the water.
John Gutierrez
Before beginning any human trials, the sponsor must perform extensive animal toxicity studies. Animal studies provide guidance on initial dosing and point to areas of safety needing special attention during human studies.
Dr. Steven Galson
We had been accumulating clues that the glutamine tract expansion is clearly what is important for disease because that's the mutation. But we also concluded that there was something else beyond the glutamine that's really mediating the toxicity of the protein.
Huda Y. Zoghbi
We're usually willing to tolerate a lot of toxicity when we're on the first round, because we're going for a cure. But when it recurs and there's no chance of a cure, we want to pick treatments based on quality of life issues.
Dr. Robert Wenham
If you are regulating on a basis of toxicity, from what we've seen, there is no basis for further regulation, ... But they are not regulating based on that.
Glenn Miller
You really have to ask the patients themselves if they think this improvement is worth the added impact of toxicity and visits to the doctor. Some patients want every day they can get; others opt for more family time.
Robert Mayer
Many doctors who treat children for autism claim they are suffering from mercury or lead toxicity. There is not sufficient evidence that autism is caused by mercury or lead toxicity.
Stephen Barrett
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