The more fat tissue there is in the buttock, the less likely the needle will reach the muscles underneath that fat.

135

There is no question that obesity is the underlying cause. We have identified a new problem related, in part, to the increasing amount of fat in patients' buttocks.

122

This results in the patient either not receiving the maximum benefit of the drug or receiving no benefit at all, because the drug levels are insufficient to have any effect.

121

People have to either lose weight, or we have to use longer needles.

108