To our surprise, three of the people that were PIB-positive and had low A-beta 42 levels were clinically normal.

In my dreams, I see 10 to 20 years from now, people who are 50 to 55 years old will get a cognitive evaluation, a PIB scan followed by a CSF test, combined with genetic markers. And the doctor will be able to tell people on an individual basis their risk for developing Alzheimer's disease.