The idea is that the radiologist would read the scan and then refer to the CAD detection and then re-review the sites that CAD pointed out and finally arrive at a diagnosis. Typically, I expect that a radiologist would not change his or her initial diagnosis, but if CAD pointed out something that the radiologist had overlooked, then the radiologist might add that detection to their diagnosis.

A number of small studies have shown that CTC with CAD is effective at finding polyps, so my goal was to do a large study to show a true expected performance of CAD, to get a better sense of whether this was near to clinical utility.