Before this study, estimates were all over the map on the transmissibility of pandemic flu.

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The earlier work focused on the potential as they saw it and the difficulties of doing it once. And we're making the suggestion that doing it once might well not be enough.

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Acute events are much more destructive if long-term planning hasn't been done, ... So it's in our interest to be concerned about controlling infections like TB even outside our own borders.

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In order to become a pandemic, it will have to change ... And we don't know what that changed strain will do.

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In normal flu years, most of us have immunity, either from the vaccine or from having the flu in previous years, ... But in pandemics, we have no prior immunity, and it's just like being hit with a completely new disease that we've never built up any ability to fight. That's why the mortality tends to be high even in the age groups that don't usually get very sick from flu.

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