Newspapers will, no doubt, also ultimately settle into their own place as the bulk provider of low-cost advertising targets.

Just to show you how perverse the markets can be, the No. 1 investment over the past 15 months was a product that is given away for free at virtually every restaurant in the world.

Biotech is one of the best groups to trade on a seasonal basis because the stocks tend to trade up in advance of or during conferences.