Women are less likely to be referred for treatment, less likely to have diagnostic tests and because they are not at this level of care are not included in trials.
The study reinforces the message that the seeds of heart disease are sown in early life, which is why it is so important to try to alter the lifestyle of our children.
The next step will be to see if the results are consistent in different populations and then test how the genetic variations are causing increased risk.
With an epidemic of obesity and associated type 2 diabetes round the corner, there is a greater need to focus on the management of chronic conditions including heart and circulatory disease.
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