Dr. Alt's discoveries have led to a greater understanding of the ways that cancers of immune cells develop and they hold promise for finding ways to control or perhaps prevent these diseases. Dr. Alt's studies of the instability of the genome are central to our understanding of the events that lead to transformation of normal cells to cancer cells.

The goal of the Translational Research Program is to provide researchers with the resources to advance diagnosis, prevention, or treatment of blood cancers in the near term. Dr. Dittmer's research may lead to earlier diagnosis, potentially prevention, and provide the insights to develop a better treatment for a particular group of lymphoma patients.

The findings were pretty striking, ... It would be a step forward in making transplant more accessible to more people, especially older people, and reducing the morbidity and mortality from acute GVHD.

What these folks are saying is that if you use this conditioning regimen, you can get very good results and you eliminate or you greatly minimize acute GVHD, ... You keep the good effects while reducing the bad.

We need replication in other studies but, if it is verified, it means there would be another approach to conditioning a patient that would greatly minimize acute GVHD but lead to the same beneficial effects.