This study is a very important reminder to physicians to pay particular attention to a woman's family history of colon, endometrial and ovarian cancers, with genetic counseling becoming of utmost importance. If women with Lynch syndrome are identified, there needs to be coordinated care between the gastrointestinal and obstetrics and gynecologic medical disciplines.

For women who have this condition and are at an extremely high risk for two gynecological cancers, this study provides a positive finding. We now have definitive evidence for doing something proactively that will prevent women with Lynch syndrome from ever getting either endometrial, or ovarian cancers, or even both.

We now have definitive evidence for doing something proactively that will prevent women with Lynch syndrome from ever getting either endometrial, or ovarian cancers, or even both.